- Recommendation basesd on reliable evidence --- this is the basic stance of Fujicco
- Two findings related to Equol
- Bone Health
- First in the world - confirmation of Bone Loss Preventing Effect by pure reagent
- Confirmation of the condition whereby: 'A person with high bone density has a high amount of urinary Isoflavones'
- By intake of Isoflavones, the urinary excretion of Bone Absorption Marker decreases
Restriction of Ca elution from bone was proven - Drinking Fujicco Tea containing Isoflavones proved the effect
- When exercise is added to intake of Isoflavones, Bone Density increases
- Walking combined with Fujiflavone intake prevents Bone Loss and reduces Body Fat
- More than 90mg Isoflavone intake increases Spine Bone Density of menopausal women
- Isoflavones promote Bone Formation
- Estrogen's Bone Mass Maintenance Mechanism made clear:
Important point of action is 'regulation of Osteoclasts life span'
- Menopausal Symptoms
- Occurrence of Hot Flashes among a group ingesting some amount of Isoflavones is less than half of that among a group taking a smaller amount
- Intake of Isoflavones prevents Atrophy of Mucosa and provides moisture
- Effect for Beautiful Skin confirmed:
Moisture maintenance・collagen creation・suppressing action against melanin
- Obesity
- Cardiovascular Diseases
- High Isoflavone Intake women group showed reduction of Cerebral and Myocardial Infarction Risk
- Isoflavone Intake lowers Blood Pressure
- Isoflavones reduce Serum Cholesterol
- Intake of 100mg Isoflavones lowers Serum Total Cholesterol and LDL Cholesterol
- A hypothesis of Isoflavones' Blood Pressure Reducing Mechanism was presented
- Cancers etc.
- Breast Cancer Mortality Rate is low in Soybean eating regions while in low Isoflavone Intake areas the mortality rate is high
- Isoflavones lower Breast Cancer Risk
- High Blood Isoflavone (Genistein) Level group shows lower Breast Cancer Incidence Rate
- Isoflavones prevent progress of Prostate Cancer
- Risk of Localized Prostate Cancer is lowered in higher Isoflavone Intake group
- High Soy Products intake group shows Mortality Rate Risk of Stomach Cancer reduced by half
- Isoflavones suppress Stress Induced Stomach Ulcer
Bone Health
Estrogen's Bone Mass Maintenance Mechanism made clear:
Important point of action is 'regulation of Osteoclasts life span'
The Japan Science and Technology Agency in a joint study with the University of Tokyo, as a result of analyzing the function of estrogen receptor in osteoclasts using genetically engineered mice in order to find causes of postmenopausal osteoporosis, made clear for the first time that estrogen by binding to estrogen receptor in osteoclasts makes genes of a factor to cause the death of cells・apoptosis (Fas Ligand) active and regulate the life span of osteoclasts.
This is the first study to find that in a vertebrate the important point of action for estrogen in the bone system is the osteoclast. It is expected that it will be useful in the future for correctly targeted developments of medicines for osteoporosis.
Cell web version; 2007.9.6
